I check the reciprocity status for my Alabama CCW permit before any road trip. I've yet to travel by car to or through any state that didn't accept my permit. So on family trips, or business trips where I drive versus fly, I'm good so far.
I've considered going through all the hoops to check a gun in a locked case when traveling by plane, but have never gone through the effort to date. Plus, some of the places I go on business travel I may be going to companies that don't permit weapons on the premises, and I wouldn't have anywhere to leave it, since half the time these days I am using Uber or Lyft.