Just curious Bob, why not? They're a non-native species and the native species typically have no learned nor inherited traits to defend from them. It's been estimated the native small mammal and reptile populations along with nesting and water birds in large parts of the glades has been decimated by about 80%+. Think about that number ... 80%+! That means possums, racoons, field and roof rats, rabbits, squirrels, pigs, Bobcats, white tailed deer, small alligators, turtles, etc, and could very well wipe out the small remaining number of endangered Florida Panthers. Also turkey, quail, and just about every other ground nesting bird.
And I've recently heard the pythons are evolving and learning to climb trees to access tree nesting birds. Sadly it's not the python's fault, but they can/will eventually totally destroy, or at least badly upset the natural balance of nature in that area. We may never, and likely will never completely rid these lands of the pythons, but we can possibly get them down to a number that the Everglades can support and control. The 'Everglades/Florida Bay System' covers an estimated 1.5 - 2 million acres. That's a lot of the state to lose to a non native species. And the only thing now keeping them from areas further north is winter temps. But over time they will evolve to a state where they can tolerate the colder temperatures.
Much like the feral pigs are doing to other parts of the country ... also a non native species that is literally destroying lots of acreage across Florida's farm and ranch land. Just a note, but feral pigs will decimate any land nesting birds in an area in short order. Quail, turkeys for instance have literally no chance in an area with pigs.
I agree with you in this, that I will not arbitrarily kill a native snake like a rattler, moccasin, or any other native snake just because I run across them in the woods. Many times I've just walked around these snakes and left them alone. I generally will kill those non native species of snakes, et al: especially those so detrimental to the native ones. Again, not preaching, just curious.