I never said Loc-Tite lubricates threads, I said they seal the threads. It anerobic, once torqued down removing any oxygen in the threads filled with loctite, it will harden and become solid, this will seal out water, salt and road grime that could work its way into the threads and cause corrosion and seizing.
I can see the argument, that on a firearm, that you are actively maintaining and preventing corrosion, there is no need to seal screws to prevent corrosion.
I've used anti-seize as well, for undercarriage, and while it will lubricate threads, it has a lot of heavy metals suspended in it that will act as a sacrificial anode to prevent corrosion on the threads. I've worried the lubricating properties of the anti-seize might allow bolts to loosen up, but I haven't seen that. I tend to use the loctite on small bolts and anti-seize on large bolts. Lubricating threads will throw off torque to clamp force values and can cause you to overtorque hardware when using torque values for dry torques. You're suppose to reduce the torque if using a torque wrench if you use anti-seize on the threads. I think its by 25%.
A lot of supplied screws for optics, including quality optics, come with loctite pre-applied to the threads. I can see the argument, that if already comes with loctite, not to use more.
Pre-appliead loctite is a different formulation than regular loctite. You can NOT put a drop of regular loctite on threads and have it harden and work the same as you see on the threads that come with loctite pre-applied, they get a different product at the factor that they use to pre-apply that loctite on threads.
Now the screws that hold the cover plate/adapter plate on the XD-M slide, they are very tiny. I have to agree with you, I would worry about the loctite being enough on such tiny screws, you could run into trouble. Personally the screws for the optic to slide/adapter plate look sturdy enough to me, I don't worry about using loctite. Perhaps if I got an optic that had smaller screws, I would worry then.